[HTML][HTML] The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease

Y Zhao, TY Wu, MF Zhao, CJ Li - Journal of Biological Chemistry, 2020 - ASBMB
… In this review, we summarize key aspects of protein prenylation … C is cysteine, a is any
aliphatic amino acid, and X is another … Proteins with cysteine residues typically found in the CaaX …

GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase

S Kuchay, H Wang, A Marzio, K Jain, H Homer… - Nature structural & …, 2019 - nature.com
proteins by these lipids at a carboxy-terminal cysteine residue, generally referred to as
prenylation, … A rabbit polyclonal antibody against the peptide corresponding to amino acids 339 to …

[HTML][HTML] … protein farnesylation system in prokaryotic cells reveals Arabidopsis AtJ3 produced and farnesylated in E. coli maintains its function of protecting proteins …

JR Wu, R Zohra, NKT Duong, CH Yeh, CA Lu, SJ Wu - Plant Methods, 2023 - Springer
… , where the “C” is cysteine for thioester linkage of the farnesyl … Anti-farnesyl antibodies
that can detect specific farnesylated … plant proteins are generally subjected to post-prenylation

[HTML][HTML] Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells

KF Suazo, A Jeong, M Ahmadi, C Brown, W Qu, L Li… - Scientific reports, 2021 - nature.com
… -box prenylation motif (C = cysteine, a and X = any amino acid) and … antibodies have not
proved to be generally useful for … the presence of lovastatin except for RhoB. Interestingly, that …

[PDF][PDF] https://www. jbc. org/cgi/doi/10.1074/jbc. REV119. 008897 The latest version is at

Y Zhao, T Wu, M Zhao, CJ Li - researchgate.net
… In this review, we summarize key aspects of protein prenylation … C: cysteine, a: any aliphatic
amino acid, and X: other amino … geranylgeranylated RhoB and farnesylated RhoB suppress …

[PDF][PDF] A targeted protein degradation cell-based screening for nanobodies selective toward the cellular RHOB GTP-bound conformation

N Bery, L Keller, M Soulie, R Gence, AL Iscache… - Cell chemical …, 2019 - cell.com
RHOB-GTP using F-box-intracellular single-domain antibody … -bound RHOB L63 missing
the last 11 amino acids involved … tween RHO isoforms appeared low in vitro, in cellulo we also …

Evaluating And Exploiting The Substrate Selectivity Of Farnesyltransferase

G Schey - 2023 - conservancy.umn.edu
… were not known to be prenylated in vivo. The best substrates were … bind a specific target as
an alternative to antibody scaffolds [27]. … amino acids except cysteine, leucine, and glutamine. …

Ubiquitin-based modifications in endothelial cell–cell contact and inflammation

J Majolée, I Kovačević, PL Hordijk - Journal of Cell Science, 2019 - journals.biologists.com
RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein:
evidenced in vivo by an anti-farnesyl cysteine antibody

[HTML][HTML] The implications for cells of the lipid switches driven by protein–membrane interactions and the development of membrane lipid therapy

M Torres, CA Rosselló, P Fernández-García… - International journal of …, 2020 - mdpi.com
prenylation of the cysteine residue of the C-terminal CaaX box, where “a” refers to an aliphatic
amino acid and “X” to any amino acid [41… in vitro and membrane microdomains in vivo [85] …

Structure-Guided Development of Antifungal Protein Farnesyltransferase Inhibitors and DNA Polymerase Engineering

Y Wang - 2021 - search.proquest.com
Protein prenylation catalyzed by protein farnesyltransferase (… C cysteine, a any aliphatic
amino acid, X any amino acid. cAMP Cyclic … RHOB is another well studied protein which can be …